Aspirin and Cancer

Standard

A low dose aspirin regimen may

  • Reduce the risk of heart attack
  • For persons over 50, reduce the risk of certain types of cancer including colorectal.

The risk associated with daily aspirin use is internal bleeding. Thus, for example, its not recommended for people with stomach ulcers. The bleeding risk increases with age, so some doctors are reluctant to recommend an aspirin regimen for people over age 60. A task force has recommended that use over age 60 be left to the individual, and be based on whether an individual is more concerned about the bleed risk or the potential benefits with regard to cancer and heart disease.


Soources:

  1. Arefa Cassoobhoy, MD, MPH, “Aspirin to Prevent Cancer: What to Tell Patients,” Medscape, 14 April 2017. http://www.medscape.com/viewarticle/878567?nlid=114187_1521&src=WNL_mdplsfeat_170418_mscpedit_wir&uac=153634BV&spon=17&impID=1330937&faf=1
  2. Mayo Clinic, “Daily aspirin therapy: Understand the benefits and risks.” http://www.mayoclinic.org/diseases-conditions/heart-disease/in-depth/daily-aspirin-therapy/ART-20046797

 

Low dose aspirin and pregnancy

Standard

The National Institutes of Health reported on a study regarding the benefit of low dose aspirin to pregnant mothers.

Low dose aspirin has been recognized as a course for reducing the risk of heart attack.

This study has an entirely different focus.  Featured Image -- 5334

C-reactive protein (CRP) can be found in the blood, and indicates the presence of inflammation in the body.

In pregnant women, CRP level is an indicator for premature uterine contractions, premature delivery and miscarriage.  As reported in one study . . .

(93) out of (100) women with premature uterine contractions had elevated level of C-Reactive protein and 91% delivered prematurely while in the control group only (9) out of (100) women had elevated level of C-reactive protein and only 8% of them delivered preterm. Differences were statistically highly significant. [Nakishbandy]

Aspirin treats inflammation. Pregnant women with inflammation who take low dose aspirin improve their chances for a successful delivery.

The CRP screen is a low-cost test, and is included in “most” standard tests during pregnancy.    Aspirin is, of course, cheap.

What to know:

The doctor needs to pay attention to CRP level.  Since the finding about low dose aspirin is new, the doctor may not be aware of it.

Standard caveat:  I’m a researcher, not a doctor.  Patients need to take an active role in healthcare in order to assure good results.  I’m trying to help by making people aware of useful information as it becomes available.  Better information should mean better conversations with your medical professionals.


Sources: