A new research study from the University of North Carolina suggests that
- There is fat in bone marrow. Higher levels are linked to weaker bone density and higher risk of fracture.
- Exercise reduces marrow fat, and causes improvement in bone mass.
- Exercise has a greater impact on the bones of obese people than those who are already lean.
- The effects can show up in a matter of weeks.
“Obesity appears to increase a fat depot in the bone, and this depot behaves very much like abdominal and other fat depots,” said Styner. “Exercise is able to reduce the size of this fat depot and burn it for fuel and at the same time build stronger, larger bones.” (1)
The research is based on a study of mice, but establishes that the cells producing fat in mouse marrow are also found in humans.
Although research in mice is not directly translatable to the human condition, the kinds of stem cells that produce bone and fat in mice are the same kind that produce bone and fat in humans. (1)
Please excuse me while I go for a jog.
- Maya Styner, Gabriel M Pagnotti, Cody McGrath, Xin Wu, Buer Sen, Gunes Uzer, Zhihui Xie, Xiaopeng Zong, Martin A Styner, Clinton T Rubin, Janet Rubin. Exercise Decreases Marrow Adipose Tissue Through ß-Oxidation in Obese Running Mice. Journal of Bone and Mineral Research, 2017; DOI: 10.1002/jbmr.3159